Index
1011
Second-order reaction, 76 
Secondary active transport, 211 
Secondary bile acids, 201 
Secondary gout, 631 
Secondary hemostasis, 839, 841 
Secondary hyperaldosteronism, 759 
Secondary hypercortisolism, 760 
Secondary hyperparathyroidism, 
8 8 6 
Secondary lysosomes, 187 
Secondary protein structure 
a-helix, 53 
/S-pleated sheets, 53 
superhelix, 56 
supersecondary, 54 
/l-turns, 53
Secondary structure, 53 
Secretin, 202, 203, 208, 505, 714 
family of hormones, 203 
Secretion, 218 
Seizures
GLUT1 and, 226 
Selectins, 143
Selection of initiation codon, 574 
Selective estrogen receptor modulators 
(SERM), 797 
Selenium, 108, 893 
Selenium deficiency, 302 
Semiconservative replication, 546, 547 
Sense strand, 566 
Separation of proteins, 36 
by chromatography, 37 
by electrophoresis, 39 
by molecular size, 37 
by solubility, 41 
isoelectric focusing, 41 
Sequence tagged sites (STSs), 539 
Sequencing DNA, 535 
SERCA, 466 
Serine, 24, 349 
Serine dehydratase, 336 
Serine proteinases, 182 
Serosa, 199
Serotonin, 147, 199, 361, 378, 700 
biosynthesis of, 362 
melatonin, 508 
SERPINS, 849, 858 
Sertoli cells, 699 
Serum albumin gene, 603 
Serum anion gap, 236 
Serum y-GT, 335 
Serum glycoproteins, 168, 170 
Serum markers, 126, 128 
Serum osmolal gap, 97 
Serum osmolality, 97 
Serum progesterone level, 793 
Serum protein electrophoresis, 949 
Serum proteins during acute phase, 954 
Serum urate, 631
Seryl hydroxyl groups, 98 
Severe acidosis, 96 
Severe combined immunodeficiency 
(SCID), 536, 635 
Severe liver disease, 282 
Severin (fragmin), 480 
Sex hormone-binding globulin, SHBG, 708 
Sex steroid pathway, 706 
Sgfl, 531 
-SH group, 230 
SH2 domain, 
8 8 6 
Shiga toxin, 223 
Shigella dysenteriae, 223 
Shine-Dalgamo sequence, 574 
Shock, 291
Short bowel syndrome, 236 
Short-chain fatty acids, 202 
Showdomycin, 316, 585 
Sialic acid (N-acetylneuraminic acid),
142, 153 
Sialidosis, 169 
Sickle cell disease, 628 
Sickle cell trait, 302, 
6 6 8 
Sickle-cell anemia, 222 
Sickling disorders, 
6 6 8 
Signal hypothesis, 580 
Signal peptidase, 580 
Signal sequences, 267 
Signal transduction, 833 
Sildenafil, 347
inhibition cGMP phosphodiesterase, 346 
Silent carrier state, 660 
Silica, 857 
Silicon, 893 
Silk fibroin, 608 
Simple acid-base disorders
classification characteristics, 937 
Simple sequence repeats (SSRs), 539 
Simvastatin, 417
Single nucleotide polymorphisms 
(SNPs), 539 
Single-displacement, 92 
Single-stranded DNA binding proteins,
552
Singlet oxygen, 305 
Sinusoids, 200 
Sister-strand exchange, 558 
Skeletal muscle, 235, 337, 339, 454, 455, 
488, 787
structure development, 454 
Skeletal muscle glycogen, 501 
Skeletal muscle metabolism 
nucleotides, 501
Skewed conformation of T4, 770 
Skin, 235, 278 
Sleep disturbances, 340 
Sleep-inducible hormones, 746 
Sliding filament model, 464
Sliding filament-rotating head 
mechanism, 467 
Slow twitch 
oxidative, 235 
Slow-twitch (ST) fiber, 462 
Sly’s syndrome, 190 
Smal, 531
Small bowel resection, 236 
Small intestine, 199, 339 
disorders of, 236
Small nuclear ribonucleoprotein particles 
(snRNPs), 85
Small nuclear ribonucleoproteins, 565 
Smith-Lemli-Opitz syndrome 
(SLO), 421 
Smooth
regulation, 472
Smooth endoplasmic reticulum, 580 
Smooth muscle, 455, 472, 473 
vascular, 473 
Sodium, 933
Sodium dodecyl sulfate, 164 
Sodium nitroprusside, 101 
Soft-tissue sarcomas, 64 
Solanum glaucophyllum (malacoxalon), 
884
Solid-phase procedure, 46 
Solutes, 2
Somatomammotropin family, 701, 737 
homology, 738
Somatomedin A (sulfation factor), 185 
Somatomedins, 185
Somatostatin, 47, 489, 490, 493, 496, 702, 
714, 734
Somatostatin growth hormone
release-inhibiting hormone, 732 
Somatostatin S (SRIH), 731 
Some abnormal, 695 
Some restriction endonucleases, 531 
Sorbitol, 139, 296, 297 
SOS DNA repair? 548 
SOS regulon, 599 
SOS repair, 559 
South African toad, 569 
Southern blot 
procedure, 533 
Southern blot analysis, 532 
Soybeans, 333 
SP1, 603
Space of disse, 200 
Spacers, 573 
Sparsomycin, 585 
Specific dynamic action (SDA), 78 
Specific dynamic action of food, 224 
Specific factor assays, 870 
Spectrin, 164, 476, 480 
binding to actin, 164 
Spectrin-actin interaction, 164